PopART/HPTN071: Universal Test and Treat for HIV Prevention

Status: Ongoing
Study Start Date: 
2013
Estimated End Date: 2017

PopART / HPTN 071 is a large community-randomised trial that will be carried out in Zambia and South Africa to measure the impact of a universal HIV test-and-treat intervention on population-level HIV incidence. To measure the impact of the intervention, a Population cohort consisting of a random sample of 2,500 adults aged 18-44 years will be selected from the general population of each cluster. A baseline survey of the cohort will be carried out at the time the intervention is initiated. Follow-up surveys of the cohort will be carried out after 12, 24 and 36 months and used to measure the impact of the intervention on HIV incidence and other outcomes.

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HPTN 071 (PopART): Rationale and design of a cluster-randomised trial of the population impact of an HIV combination prevention intervention including universal testing and treatment – a study protocol for a cluster randomised trial
Hayes R, Ayles H, Beyers N, Sabapathy K, Floyd S, Shanaube K, Bock P, Griffith S, Moore A, Watson-Jones D, Fraser C, Vermund SHFidler S, HPTN 071 (PopART): Rationale and design of a cluster-randomised trial of the population impact of an HIV combination prevention intervention including universal testing and treatment–a study protocol for a cluster randomised trial. Trials. 2014 Feb 13;15(1):1. 

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